The 21st Amendment Bar at La Louisiane in New Orleans' French Quarter celebrates Prohibition-era history with immersive decor featuring iconic mobster imagery and speakeasy aesthetics. Located at 725 Iberville Street, the intimate venue offers craft cocktails and live music without cover charge, often featuring local jazz talent. The bar is known as a welcoming escape from Bourbon Street's intensity, with a private hotel entrance adding to its hidden-gem appeal. Operating Monday-Wednesday 6 PM-midnight and Thursday-Sunday 3 PM-midnight, it received USA TODAY's Reader's Choice Award for best speakeasy in 2025.
